seren_

research intelligence workspace

Research,
with the lights on.

Bloomberg terminal for scientific knowledge — a real-time, structured map of what's actually known, contested, and unknown across fields, so that researchers, companies, and governments can make decisions grounded in the true state of evidence.

Open workspace →

Free for individual researchers · No credit card required

the workspace

Everything a researcher needs.
From hypothesis to final draft.

One workspace. Every stage of the research lifecycle. Nothing separate, nothing disconnected.

Hypothesis Tree
HSC AAV6 vs lentiviral
CD34+ tropism limits dose
Ex vivo → in vivo translation
BM-HSC matched conditions

9 papers · last updated 2h ago
Evidence Foundation
Dever et al., 201696
Nature Methods · directly addresses
Romero et al., 201988
Blood · matched protocol
Naldini et al., 202171
Cell · contradicts dose assumption
Analysis Library9 methods
Theory MapperMethod AuditorEvolution TimelineQuote MinerWeakness ScannerBridge BuilderReplication AuditFuture AgendaJargon Translator

seren_ > Running Theory Mapper against 9 papers...
→ 2 dominant frameworks identified · 1 unacknowledged tension
Mechanisms
Capsid entrystrong
Naldini 2022 · confirmed
Integrationstrong
Aiuti 2022 · confirmed
Innate sensingbuilding
2 papers · contested
Dose curveunknown
no published data
Research Terminal
you_ > /find papers on CD34 engraftment
→ 8 papers · 3 relevant · added
you_ > /add mechanism capsid tropism
→ logged · linked to root
you_ > /decision proceed AAV6
→ recorded · confidence: high
type a command or paste a DOI...
Research Proposal
Specific Aimscomplete
Background & Significancecomplete
Innovationdraft
Approach — Aim 1outline
Approach — Aim 2not started

Aim 1 references 6 papers from foundation
Data Artifacts
csvflow_cyto_run3.csv2.1 MB · 847 events⚠ QC flag col 7
xlsxengraftment_week6.xlsxn=24 · primary endpoint✓ clean

seren_ > QC flag in run3 affects 12% of events — exclude col 7 before comparison?
Uncertainty Map
Known
AAV6 efficiency
Integration fidelity
Contested
Dose translation
Innate sensing
Unknown
BM-HSC matched
Critical gap
Writing Review
§2.1 — unsupported claim
unsupported
"...well-established safety profile..." — no citation. Naldini 2021 should support.
§3.2 — contradicts decision log
contradiction
Claims BM-HSC data exists. Uncertainty map flags this as unknown.
Monitoring2 new
Mimitou et al., 2025 — newAddresses your BM-HSC gap directly · review
Schiroli et al., 2025 — newContradicts Naldini 2021 on dose curve · review
1 paper in foundation retractedReview required · flag
Decision Log
Mar 8, 2025
Proceed with AAV6 ex vivo protocol
Confidence High · Dever 2016 · Romero 2019
Feb 22, 2025
Exclude mobilised HSCs from Phase 1
Confidence Medium · Aiuti 2022

Evidence snapshot frozen at decision time

what makes seren different

Zotero / Mendeley

Stores your papers. Organises your library. Tells you nothing about what the collection means for your question.

Seren connects every paper to your hypothesis.

Elicit / Consensus

Summarises papers. Finds relevant results. Produces outputs with no memory of your specific question or what you decided.

Seren tracks what you decided and builds a permanent record.

ChatGPT / Claude

Answers questions. Starts fresh every session. Has no knowledge of your specific study, your hypothesis tree, or your prior decisions.

Seren is a persistent workspace that remembers every hypothesis.

A hypothesis mapped against the evidence.

Contested claims named and explained.

Decisions logged with the reasoning behind them.

A workspace that remembers what you built.

Finally a tool that treats my research question as the starting point, not an afterthought.

— Postdoctoral researcher, biomedical sciences

Start with
your research question.

Free for individual researchers.

Open workspace — it's free →